One step ahead of HIV

Discovering a mutating virus is very difficult. It is as difficult as”Like looking for a needle in a haystack.”

That’s the kind of difficult detective work Abbott’s Virus Hunters deal with every single day as they observe down mutating viruses from across the globe.

By growing new techniques and utilizing subsequent generation sequencing, this group recently introduced the discovery of a new strain of HIV or human immunodeficiency virus.

Abbott’s announcement of the discovery, published in the Journal of Acquired Immune Deficiency Syndromes (JAIDS), marks the first time a new subtype of HIV-1 has been recognized in nearly twenty years.

Known as HIV-1 Group M, sub type L, this new HIV subtype is a part of the same group of viruses responsible for the worldwide HIV pandemic, which has contaminated 75 million people so far and claimed an estimated 32 million lives.

“This discovery reminds us that to end the HIV pandemic, we should continue to out think this constantly altering virus and use the most recent developments in technology and sources to monitor its evolution,” says Carole McArthur,

Discovering one in a billion

Discovery of this new HIV strain culminated a process that started practically four decades ago.

To find out whether or not an uncommon virus is actually a new HIV subtype, three instances have to be found independently.

The first two samples of this sub type have been found within the Democratic Republic of Congo (DRC) in the 1980s and the 1990s. The third, collected in 2001, was troublesome to sequence at the moment due to the amount of virus within the pattern and the present technology.

At present next-generation sequencing expertise permits researchers to construct a complete genome at increased speeds and decreased prices.

Abbott scientists needed to develop and apply new strategies with a view to leverage subsequent generation sequencing, which helped narrow in on the virus portion of the sample to fully sequence and complete the genome.

“Figuring out new viruses equivalent to this one is like looking for a needle in a haystack,” says Mary Rodgers, Ph.D., a principal scientist and head of Abbott’s Global Viral Surveillance Program, and one of the study authors.

“By advancing our strategies and utilizing next-generation sequencing expertise, we’re pulling the needle out with a magnet.”

“We’re making this new strain accessible to the analysis group to guage its influence to diagnostic testing, therapies and potential vaccines.”

Twenty-five years of hunting viruses throughout the globe

Abbott created its Global Viral Surveillance Program 25 years ago to observe HIV and hepatitis viruses and establish mutations, which helps ensure the company’s diagnostic checks stay updated.

“The discovery of this new strain of HIV reminds us of why the work we do at Abbott is so essential. If we are able to prevent even one individual from turning into infected with HIV or hepatitis, then we have accomplished our jobs.”

All the developments accomplished in the discipline of medicine is by far at all times helped the mankind. The invention of latest strain HIV virus would assist medical experts to find options faster and save the lives of many. Those who have contracted this disorder or who may have the traces of this virus might get treated better and early detection would help cure the disorder faster.





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